EFFECTS OF STIMULUS VELOCITY AND ACCELERATION ON SMOOTH-PURSUIT IN MOTOR-NEURON DISEASE

被引：12

作者：

ABEL, LA ^{[1
]}

WILLIAMS, IM ^{[1
]}

GIBSON, KL ^{[1
]}

LEVI, L ^{[1
]}

机构：

[1] MONASH UNIV,ALFRED HOSP,DEPT MED,NEUROOPHTHALMOL LAB,MELBOURNE,VIC,AUSTRALIA

来源：

JOURNAL OF NEUROLOGY | 1995年 / 242卷 / 07期

关键词：

MOTOR NEURON DISEASE; EYE MOVEMENTS; GAIN; ACCELERATION;

D O I：

10.1007/BF00873543

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Sinusoidal smooth pursuit eye movements were evaluated in 11 normals, five moderately and four severely affected motor neuron disease (MND) patients, using two target amplitudes and a range of frequencies. This enabled us to examine separately the effects of peak target velocity and acceleration on pursuit gain. Moderately affected patients showed an acceleration, but not a velocity saturation; severely impaired patients' performance declined with increased velocity. Smooth pursuit eye movements are thus impaired in MND, but the nature of this pursuit deficit is complex and changes with the progression of the disease.

引用

页码：419 / 424

页数：6

共 24 条

[1] ASYMMETRIC SMOOTH PURSUIT IMPAIRMENT AND NYSTAGMUS IN MOTOR-NEURON DISEASE [J].

ABEL, LA ;

GIBSON, K ;

WILLIAMS, IM ;

LI, CW .

NEURO-OPHTHALMOLOGY, 1992, 12 (04) :197-206

[2]

ABEL LA, 1988, NEUROPSYCHOLOGY EYE

[3] CENTRAL NERVOUS SYSTEM IN MOTOR NEURONE DISEASE [J].

BROWNELL, B ;

OPPENHEIMER, DR ;

HUGHES, JT .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1970, 33 (03) :338-+

[4] SMOOTH PURSUIT DYSFUNCTION IN ALZHEIMERS-DISEASE [J].

FLETCHER, WA ;

SHARPE, JA .

NEUROLOGY, 1988, 38 (02) :272-277

[5] OCULAR MOTOR FUNCTION IN MOTOR-NEURON DISEASE [J].

GIZZI, M ;

DIROCCO, A ;

SIVAK, M ;

COHEN, B .

NEUROLOGY, 1992, 42 (05) :1037-1046

[6] MAGNETIC-RESONANCE IMAGING IN AMYOTROPHIC LATERAL SCLEROSIS [J].

GOODIN, DS ;

ROWLEY, HA ;

OLNEY, RK .

ANNALS OF NEUROLOGY, 1988, 23 (04) :418-420

[7] AN EYE-MOVEMENT DISORDER IN AMYOTROPHIC LATERAL SCLEROSIS [J].

JACOBS, L ;

BOZIAN, D ;

HEFFNER, RR ;

BARRON, SA .

NEUROLOGY, 1981, 31 (10) :1282-1287

[8] A Control Systems Model of Smooth Pursuit Eye Movements with Realistic Emergent Properties [J].

Krauzlis, R. J. ;

Lisberger, S. G. .

NEURAL COMPUTATION, 1989, 1 (01) :116-122

[9] NYSTAGMUS IN MOTOR NEURON DISEASE - CLINICOPATHOLOGICAL STUDY OF 2 CASES [J].

KUSHNER, MJ ;

PARRISH, M ;

BURKE, A ;

BEHRENS, M ;

HAYS, AP ;

FRAME, B ;

ROWLAND, LP .

ANNALS OF NEUROLOGY, 1984, 16 (01) :71-77

[10]

Leigh R.J., 1991, NEUROLOGY EYE MOVEME

← 1 2 3 →