ELECTRICAL STIMULATION OF MIDBRAIN RAPHE - BIOCHEMICAL, BEHAVIORAL AND BIOELECTRICAL EFFECTS

被引：120

作者：

KOSTOWSKI, W

GIACALONE, E

GARATTINI, S

VALZELLI, L

机构：

[1] Istituto di Recerche Farmacologiche Mario Negri

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY | 1969年 / 7卷 / 02期

关键词：

D O I：

10.1016/0014-2999(69)90006-5

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Electrical stimulation of MR in rats induces a marked increase of 5HIAA and a decrease of 5HT in the forebrain. At the same time the onset of electroencephalographic pattern of sleep and behavioral signs of calmness were observed. The most intense biochemical effects were obtained with 10 c/sec stimulation whereas 2 c/sec stimulation produced the clearest behavioral depression.{A table is presented}. © 1969.

引用

页码：170 / +

页数：1

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