EVALUATION OF 2 POSSIBLE TRANSITION-STATES IN INTRAMOLECULAR OXETANE OXOLANE RING FORMATION BASED ON AM1 CALCULATIONS

被引：6

作者：

NISHIYAMA, S

YAMAMURA, S

KATO, K

NAGAI, M

TAKITA, T

TERADA, Y

机构：

[1] KEIO UNIV,FAC SCI & TECHNOL,DEPT CHEM,YOKOHAMA,KANAGAWA 223,JAPAN

[2] NIPPON KAYAKU CO LTD,PHARMACEUT GRP,RES LABS,KITA KU,TOKYO 115,JAPAN

[3] MEIJO UNIV,FAC PHARM,TEMPAKU KU,NAGOYA,AICHI 468,JAPAN

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 33期

关键词：

D O I：

10.1016/S0040-4039(00)97731-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

AM1 calculations have been successfully carried out to evaluate relative stabilities of the two possible transition states (4-exo- and 5-endo-openings) in each intramolecular cyclization of four 3,4-epoxy alcohols, suggesting that two cis-epoxy alcohols give rise to the corresponding oxetanes while the tetrahydrofurans are only produced in the case of trans-epoxy alcohols. © 1990.

引用

页码：4777 / 4780

页数：4

共 7 条

[1] INHIBITION OF INFECTIVITY OF HUMAN-IMMUNODEFICIENCY-VIRUS BY OXETANOCIN [J].