学术探索
学术期刊
新闻热点
数据分析
智能评审

IDENTIFICATION AND NUCLEOTIDE-SEQUENCE DETERMINATION OF THE GENE RESPONSIBLE FOR OGAWA SEROTYPE SPECIFICITY OF VIBRIO-CHOLERAE 01

被引：8
作者：
ITO, T
OHSHITA, Y
HIRAMATSU, K
YOKOTA, T
机构：
[1] Department of Bacteriology, Faculty of Medicine, Juntendo University, Hongo, Bunkyo-ku, Tokyo
来源：
FEBS LETTERS | 1991年 / 286卷 / 1-2期
关键词：
O-ANTIGEN; SEROTYPE OGAWA; VIBRIO-CHOLERAE; BIOSYNTHESIS OF LIPOPOLYSACCHARIDE; SEQUENCE; DELETION PLASMID;
D O I：
10.1016/0014-5793(91)80964-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The gene encoding a protein of 27 kDa, which is specifically expressed in Vibrio cholerae of serotype Ogawa, was identified and its nucleotide sequence determined. The plasmid carrying this gene was found to convert serotype specificity from Inaba to Ogawa when introduced into the Escherichia coli DH5(pVCI112) cell which harbors a cloned 20-kilobase genomic DNA fragment of V. cholerae NIH35A3 and expresses the 01 antigen of Inaba serotype.
引用
收藏
页码：159 / 162
页数：4
相关论文
共 15 条
12