AN ALTERNATIVE SOLID-PHASE APPROACH TO C-1-OXYTOCIN

被引：29

作者：

MAYER, JP

HEIL, JR

ZHANG, JG

MUNSON, MC

机构：

[1] Amgen Boulder Inc., Boulder, CO 80301

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 41期

关键词：

D O I：

10.1016/0040-4039(95)01548-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A general, solid-phase method based on in situ formation of a cystathionine residue is described. The procedure allows for the introduction of a thioether moiety in place of a native disulfide bond and is illustrated here by the synthesis of C-1-oxytocin 1.

引用

收藏

页码：7387 / 7390

页数：4

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