A COMPLEX PYRROLO-OXAZINONE AND ITS IODO DERIVATIVE ISOLATED FROM A TUNICATE

被引：87

作者：

YOSHIDA, WY ^{[1
]}

LEE, KK ^{[1
]}

CARROLL, AR ^{[1
]}

SCHEUER, PJ ^{[1
]}

机构：

[1] UNIV HAWAII,DEPT CHEM,2545 THE MALL,HONOLULU,HI 96822

来源：

HELVETICA CHIMICA ACTA | 1992年 / 75卷 / 05期

关键词：

D O I：

10.1002/hlca.19920750525

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two cytotoxic triphenylpyrrolo-oxazinones were isolated from a tunicate and their structures elucidated by spectral methods. Lukianol A (= 3,7,8-tris(4-hydroxyphenyl)pyrrolo[2,1-c][1,4]oxazin-1 (1H)-one; 1) had MIC of 1-mu-g/ml in KB cytotoxicity tests; MIC value for 2 was 100-mu-g/ml.

引用

页码：1721 / 1725

页数：5

共 7 条

[1] METABOLITIES OF THE MARINE PROSOBRANCH MOLLUSK LAMELLARIA SP
ANDERSEN, RJ
FAULKNER, DJ
HE, CH
VANDUYNE, GD
CLARDY, J
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (19) : 5492 - 5495
[2] STEREOSTRUCTURES OF GEODIAMOLIDE-A AND GEODIAMOLIDE-B, NOVEL CYCLODEPSIPEPTIDES FROM THE MARINE SPONGE GEODIA SP
CHAN, WR
TINTO, WF
MANCHAND, PS
TODARO, LJ
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1987, 52 (14) : 3091 - 3093
[3] NOVEL PYRROLES FROM THE OREGON RED ALGA GRACILARIOPSIS-LEMANEIFORMIS
JIANG, ZD
GERWICK, WH
[J]. JOURNAL OF NATURAL PRODUCTS, 1991, 54 (02): : 403 - 407
[4] NEW ALKALOIDS OF THE LAMELLARIN CLASS FROM THE MARINE ASCIDIAN DIDEMNUM-CHARTACEUM (SLUITER, 1909)
LINDQUIST, N
FENICAL, W
VANDUYNE, GD
CLARDY, J
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1988, 53 (19) : 4570 - 4574
[5] RAHMAN A, 1986, NUCLEAR MAGNETIC RES, pCH4
[6] PERAMINE, A NOVEL INSECT FEEDING DETERRENT FROM RYEGRASS INFECTED WITH THE ENDOPHYTE ACREMONIUM-IOLIAE
ROWAN, DD
HUNT, MB
GAYNOR, DL
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1986, (12) : 935 - 936
[7] NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY . CARBON-13 SPECTRA OF 5-MEMBERED AROMATIC HETEROCYCYCLES
WEIGERT, FJ
ROBERTS, JD
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1968, 90 (13) : 3543 - &

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