ASYMMETRIC-SYNTHESIS OF UNUSUAL AMINO-ACIDS - SYNTHESIS OF THE OPTICALLY PURE ISOMERS OF INDOLE-PROTECTED BETA-METHYLTRYPTOPHAN SUITABLE FOR PEPTIDE-SYNTHESIS

被引：36

作者：

BOTEJU, LW ^{[1
]}

WEGNER, K ^{[1
]}

HRUBY, VJ ^{[1
]}

机构：

[1] UNIV ARIZONA,DEPT CHEM,TUCSON,AZ 85721

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 49期

关键词：

D O I：

10.1016/S0040-4039(00)60804-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The four isomers of N-indole-(2-mesitylenesulfonyl)-beta-methyltryptophan have been synthesized in high optical purity using in part, asymmetric conjugate 1, 4-additions followed by chiral imide enolate azidation and reduction.

引用

页码：7491 / 7494

页数：4

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