EFFECT OF INTERLEUKIN-2 ON INTRACTABLE HERPES-VIRUS INFECTION AND CHRONIC ECZEMATOID DERMATITIS IN A PATIENT WITH WISKOTT-ALDRICH SYNDROME

被引：15

作者：

AZUMA, H

SAKATA, H

SAIJYOU, M

OKUNO, A

机构：

[1] Department of Paediatrics, Asahikawa Medical College, Asahikawa

来源：

EUROPEAN JOURNAL OF PEDIATRICS | 1993年 / 152卷 / 12期

关键词：

RECOMBINANT IL2; WISKOTT-ALDRICH SYNDROME; ATOPIC DERMATITIS; HERPES VIRUS INFECTION;

D O I：

10.1007/BF01957224

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Recombinant interleukin 2 (rIL2) was administered to a patient with Wiskott-Aldrich syndrome for the treatment of an intractabel facial herpetiforme lesion. This treatment appeared to be effective in suppressing the virus activity. At the same time, a transient improvement of the chronic eczematoid dermatitis was observed. During rIL2 administration, the CD3+ and CD4+ subsets of peripheral blood lymphocytes increased in number. These changes might play an important role in the induction of anti-viral immunity and in the improvement of dermatits.

引用

页码：998 / 1000

页数：3

共 15 条

[1]

BICHTHUY LT, 1987, J IMMUNOL, V139, P1550

[2]

CHIEN CH, 1990, PEDIATRICS, V86, P937

[3] ADHESIVE AND DEGRADATIVE PROPERTIES OF HUMAN PLACENTAL CYTOTROPHOBLAST CELLS-INVITRO [J].