CURRENT-DENSITY ANALYSIS OF OUTWARD CURRENTS IN ACUTELY ISOLATED RAT ENTORHINAL CORTEX CELLS

被引：13

作者：

EDER, C ^{[1
]}

HEINEMANN, U ^{[1
]}

机构：

[1] HUMBOLDT UNIV BERLIN,INST PHYSIOL CHARITE,NEUROPHYSIOL ABT,D-10115 BERLIN,GERMANY

来源：

NEUROSCIENCE LETTERS | 1994年 / 174卷 / 01期

关键词：

A-CURRENT; DELAYED RECTIFIER CURRENT; CA2+-ACTIVATED K+ CURRENT; ENTORHINAL CORTEX; PYRAMIDAL CELL; STELLATE CELL; RAT PUP;

D O I：

10.1016/0304-3940(94)90118-X

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Entorhinal cortex stellate and pyramidal cells were acutely isolated from juvenile rats. Using the whole-cell configuration of the patch-clamp method outward potassium currents were recorded. A fast transient A-current and a sustained outward current could be measured in both stellate and pyramidal cells. The A-current density was significantly larger in pyramidal cells than in stellate cells. In contrast, stellate cells possessed a larger current density of the delayed rectifier current as well as the Ca2+ activated K+ current than pyramidal cells. Moreover, superficial stellate cells exhibited large delayed rectifier currents and only small A-currents while entorhinal cortex deep layer pyramidal cells displayed larger A-currents than delayed rectifier currents.

引用

页码：58 / 60

页数：3

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