COMPARISON OF X-PROLYL DIPEPTIDYL-AMINOPEPTIDASE ACTIVITY IN HUMAN CEREBROSPINAL-FLUID WITH THAT IN SERUM

被引：15

作者：

KATO, T

IWASE, K

NAGATSU, T

SAKAKIBARA, S

FUJITA, K

机构：

[1] TOKYO INST TECHNOL,GRAD SCH NAGATSUTA,DEPT LIFE CHEM,CELL PHYSIOL LAB,YOKOHAMA 227,JAPAN

[2] PROT RES FDN,PEPTIDE INST,MINOH,OSAKA 562,JAPAN

[3] FUJITA GAKUEN UNIV,SCH MED,TOYOAKE,AICHI 47011,JAPAN

来源：

EXPERIENTIA | 1979年 / 35卷 / 01期

关键词：

D O I：

10.1007/BF01917849

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

X-Prolyl dipeptidyl-aminopeptidase activities in cerebrospinal fluid and serum from the same patients without neurological diseases, undergoing surgery under lumbar anesthesia, were assayed fluorometrically with a newly synthesized fluorogenic substrate, 7-glycylproline-4-methylcoumarinamide; the values were 129.1±19.5 nmoles/min/1 and 54.17±3.11 μmoles/min/1 (mean±SEM, n=23), respectively, and there was no correlation between both activities (r=0.0894). © 1979 Birkhäuser Verlag.

引用

页码：20 / 21

页数：2

共 13 条

[1]

BARTH A, 1974, ACTA BIOL MED GER, V32, P157

[2] A NEW DIPEPTIDE NAPHTHYLAMIDASE HYDROLYZING GLYCYL-PROLYL-BETA-NAPHTHYLAMIDE [J].