A STUDY OF SOME 1-ALKYL-2,3-DIHYDROIMIDAZO[1,2-ALPHA]BENZIMIDAZOLES

被引：20

作者：

NORTH, RJ

DAY, AR

机构：

[1] Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1969年 / 6卷 / 05期

关键词：

D O I：

10.1002/jhet.5570060511

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of 1‐alkyl‐7‐nitro (and 7‐amino)‐2,3‐dihydroimidazo[1,2‐α]benzimidazoles has been prepared. Similarly, a series of 1‐alkyl‐2,3‐dihydroimidazo[1,2‐α]benzimidazoles has been prepared. The prototropic tautomerism of this system has been studied. The site of electrophilic attack (alkylation) has been examined. 1‐Alkylation takes place under strongly basic conditions and 9‐alkylation occurs under neutral conditions. Copyright © 1969 Journal of Heterocyclic Chemistry

引用

页码：655 / &

共 25 条

[1] REDUCTIONS WITH HYDRAZINE HYDRATE CATALYZED BY RANEY NICKEL .1. AROMATIC NITRO COMPOUNDS TO AMINES [J].

BALCOM, D ;

FURST, A .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1953, 75 (17) :4334-4334

[2] GUANIDINE COMPOUNDS .2. PREPARATION OF MONO-ALKYLGUANIDINES AND N,N-DI-ALKYLGUANIDINES [J].

BANNARD, RAB ;

CASSELMAN, AA ;

COCKBURN, WF ;

BROWN, GM .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1958, 36 (11) :1541-1549

[3]

BATES RG, 1964, DETERMINATION PH, pCH7

[4]

BATES RG, 1964, DETERMINATION PH, pCH8

[5]

BIRD CW, 1964, CHEM IND LONDON, P5284

[6]

BIRD CW, 1963, CHEM IND LONDON, P1157

[7]

DONALDSON CW, 1967, THESIS U PENNSYLVANI

[8] SYNTHESES OF 1,4-DIAZABICYCLO[4.4.0]DECANES, 1,4-DIAZABICYCLO[4.3.0]NONANES AND 1,8-DIAZABICYCLO[4.3.0]NONANES [J].

FREED, ME ;

DAY, AR .

JOURNAL OF ORGANIC CHEMISTRY, 1960, 25 (12) :2108-2113

[9]

FREEDMAN AR, 1962, THESIS U PENNSYLVANI

[10] REDUCTIONS WITH HYDRAZINE HYDRATE CATALYZED BY RANEY NICKEL .2. AROMATIC NITRO COMPOUNDS TO INTERMEDIATE PRODUCTS [J].

FURST, A ;

MOORE, RE .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1957, 79 (20) :5492-5493

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