OBSERVATION OF TISSUE PROKALLIKREIN ACTIVATION BY SOME SERINE PROTEASES, ARGININE ESTERASES IN RAT SUBMANDIBULAR-GLAND

被引：16

作者：

KAMADA, M

FURUHATA, N

YAMAGUCHI, T

IKEKITA, M

KIZUKI, K

MORIYA, H

机构：

[1] Department of Biochemistry, Faculty of Pharmaceutical Sciences, Science University of Tokyo, Tokyo

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1990年 / 166卷 / 01期

关键词：

D O I：

10.1016/0006-291X(90)91935-L

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two serine proteases, arginine esterases (esterases I and II) which showed the activity of tissue prokallikrein activation were identified in rat submandibular gland. These enzymes were separated from the homogenate of rat submandibular gland by two successive DEAE-cellulose chromatographies and were further purified and characterized. Esterases I and II were found to be identical with tonin and esterase B-like enzyme, respectively. Both enzymes activated rat urinary prokallikrein at near neutral pH. Esterase B-like enzyme activated rat urinary prokallikrein better than tonin. © 1990.

引用

页码：231 / 237

页数：7

共 13 条

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[2]

DERMASSIEUX S, 1976, CAN J BIOCHEM, V9, P788

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