SELECTIVE IMMUNODEFICIENCY AND MALIGNANT-LYMPHOMA OF THE CENTRAL NERVOUS-SYSTEM - POSSIBLE RELATIONSHIP TO THE EPSTEIN-BARR-VIRUS

被引:35
作者
PATTENGALE, PK
TAYLOR, CR
PANKE, T
TATTER, D
MCCORMICK, RA
RAWLINSON, DG
DAVIS, RL
机构
[1] UNIV SO CALIF,SCH MED,DEPT PATHOL,LOS ANGELES,CA 90033
[2] UNIV SO CALIF,SCH MED,DEPT NEUROL,LOS ANGELES,CA 90033
[3] UNIV SO CALIF,LOS ANGELES CTY MED CTR,NEUROMED SERV,LOS ANGELES,CA 90033
[4] UNIV SO CALIF,LOS ANGELES CTY MED CTR,CAJAL LAB NEUROPATHOL,AUTOPSY UNIT,LOS ANGELES,CA 90033
关键词
Central nervous system; Epstein-Barr virus; Infectious mononucleosis; Malignant lymphoma;
D O I
10.1007/BF00690516
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
This report presents the findings of a study of a 17-year-old male with a selective immunodeficiency to the Epstein-Barr virus, who died of a malignant lymphoma following clinical infectious mononucleosis. Autopsy findings and immunohistochemical techniques demonstrated a malignant lymphoma with B-lymphocyte characteristics which primarily involved the central nervous system (CNS). The relationship of the Epstein-Barr virus to lymphoproliferation is discussed. © 1979 Springer-Verlag.
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页码:165 / 169
页数:5
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