DEPSIDONE SYNTHESIS .14. TOTAL SYNTHESIS OF PSOROMIC ACID - ISOPROPYL ETHERS AS USEFUL PHENOLIC PROTECTIVE GROUPS

被引：91

作者：

SALA, T ^{[1
]}

SARGENT, MV ^{[1
]}

机构：

[1] UNIV WESTERN AUSTRALIA,DEPT ORGAN CHEM,NEDLANDS 6009,W AUSTRALIA,AUSTRALIA

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1979年 / 10期

关键词：

D O I：

10.1039/p19790002593

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The total synthesis of 4-formyl-3-hydroxy-8-methoxy-1,9-dimethyl-11-oxo- 11H-dibenzo[b,e][1,4]dioxepin-6-carboxylic acid (psoromic acid) (28), a lichen depsidone, by selective functionalization of synthetic methyl 3,8-dimethoxy-1,4,9-trimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-6- carboxylate (methyl O-methylhypopsoromate) (23) and subsequent steps, is described. Attention is drawn to the use of isopropyl ethers as phenol protective groups.

引用

页码：2593 / 2598

页数：6

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