REARRANGEMENT REACTIONS OF TAXANES - STRUCTURAL MODIFICATIONS OF 10-DEACETYLBACCATIN-III

被引：75

作者：

WAHL, A ^{[1
]}

GUERITTEVOEGELEIN, F ^{[1
]}

GUENARD, D ^{[1
]}

LEGOFF, MT ^{[1
]}

POTIER, P ^{[1
]}

机构：

[1] CNRS,INST CHIM SUBSTANCES NAT,F-91198 GIF SUR YVETTE,FRANCE

来源：

TETRAHEDRON | 1992年 / 48卷 / 34期

关键词：

D O I：

10.1016/S0040-4020(01)91208-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

10-Deacetylbaccatin III 2 is a taxane diterpenoid isolated from the plant genus Taxus, which has been used for the partial synthesis of the antitumor compounds taxol and taxotere(R). A number of structural modifications have been performed on 2 under acidic and basic conditions in order to obtain new synthetic precursors of taxol and taxotere(R) analogues.

引用

页码：6965 / 6974

页数：10

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