Recent Advances in Biomaterials for 3D Printing and Tissue Engineering

被引:389
作者
Jammalamadaka, Udayabhanu [1 ]
Tappa, Karthik [1 ]
机构
[1] Washington Univ, Sch Med, Mallinckrodt Inst Radiol, St Louis, MO 63110 USA
关键词
three-dimensional printing; additive manufacturing; bioprinting; biomaterials; bioinks; ceramics; polymers; composites; tissue engineering;
D O I
10.3390/jfb9010022
中图分类号
R318 [生物医学工程];
学科分类号
0831 [生物医学工程];
摘要
Three-dimensional printing has significant potential as a fabrication method in creating scaffolds for tissue engineering. The applications of 3D printing in the field of regenerative medicine and tissue engineering are limited by the variety of biomaterials that can be used in this technology. Many researchers have developed novel biomaterials and compositions to enable their use in 3D printing methods. The advantages of fabricating scaffolds using 3D printing are numerous, including the ability to create complex geometries, porosities, co-culture of multiple cells, and incorporate growth factors. In this review, recently-developed biomaterials for different tissues are discussed. Biomaterials used in 3D printing are categorized into ceramics, polymers, and composites. Due to the nature of 3D printing methods, most of the ceramics are combined with polymers to enhance their printability. Polymer-based biomaterials are 3D printed mostly using extrusion-based printing and have a broader range of applications in regenerative medicine. The goal of tissue engineering is to fabricate functional and viable organs and, to achieve this, multiple biomaterials and fabrication methods need to be researched.
引用
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页数:14
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