SIMULTANEOUS DETERMINATION OF PLANAR CHLOROBIPHENYLS AND POLYCHLORINATED DIBENZO-P-DIOXINS AND DIBENZO-P-FURANS IN DUTCH MILK USING ISOTOPE-DILUTION AND GAS-CHROMATOGRAPHY HIGH-RESOLUTION MASS-SPECTROMETRY

被引：25

作者：

VANRHIJN, JA ^{[1
]}

TRAAG, WA ^{[1
]}

VANDESPRENG, PF ^{[1
]}

TUINSTRA, LGMT ^{[1
]}

机构：

[1] DLO,STATE INST QUAL CONTROL AGR PROD,BORNESTEEG 45,6708 PD WAGENINGEN,NETHERLANDS

来源：

JOURNAL OF CHROMATOGRAPHY | 1993年 / 630卷 / 1-2期

关键词：

D O I：

10.1016/0021-9673(93)80466-L

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A method is described for the simultaneous determination of planar chlorobiphenyls and dioxins in milk using isotope dilution and gas chromatography-high-resolution mass spectrometry (GC MS). The method is based on gel permeation chromatography, alumina clean-up and carbon chromatography and is highly automated, making a high sample throughput possible. Data on recovery, accuracy and reproducibility of results obtained with quality control samples are presented. Data for both dioxins and planar chlorbiphenyls from the analysis of samples of Dutch milk from several areas in the Netherlands are also presented. Possible interference of the chlorobiphenyls in the determination of the dioxins in the GC-MS method is discussed.

引用

页码：297 / 306

页数：10

共 11 条

[1] ANALYSIS OF POLYCHLORINATED-BIPHENYLS (PCB) BY GLASS-CAPILLARY GAS-CHROMATOGRAPHY - COMPOSITION OF TECHNICAL AROCLOR-PCB AND CLOPHEN-PCB MIXTURES [J].

BALLSCHMITER, K ;

ZELL, M .

FRESENIUS ZEITSCHRIFT FUR ANALYTISCHE CHEMIE, 1980, 302 (01) :20-31

[2] ISOMER-SPECIFIC ANALYSIS OF PCBS INCLUDING TOXIC COPLANAR ISOMERS IN CANNED COD LIVERS COMMERCIALLY PROCESSED IN POLAND [J].

FALANDYSZ, J ;

YAMASHITA, N ;

TANABE, S ;

TATSUKAWA, R .

ZEITSCHRIFT FUR LEBENSMITTEL-UNTERSUCHUNG UND-FORSCHUNG, 1992, 194 (02) :120-123

[3] SEPARATION OF PURE POLYCHLORINATED BIPHENYL ISOMERS INTO 2 TYPES OF INDUCERS ON BASIS OF INDUCTION OF CYTOCHROME-P-450 OR P-448 [J].

GOLDSTEIN, JA ;

HICKMAN, P ;

BERGMAN, H ;

MCKINNEY, JD ;

WALKER, MP .

CHEMICO-BIOLOGICAL INTERACTIONS, 1977, 17 (01) :69-87

[4] COPLANAR PCBS IN FISH AND MUSSELS FROM MARINE AND ESTUARINE WATERS OF NEW-YORK-STATE [J].

HONG, CS ;

BUSH, B ;

XIAO, J .

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 1992, 23 (01) :118-131

[5] ENVIRONMENTAL OCCURRENCE, ABUNDANCE, AND POTENTIAL TOXICITY OF POLYCHLORINATED BIPHENYL CONGENERS - CONSIDERATIONS FOR A CONGENER-SPECIFIC ANALYSIS [J].

MCFARLAND, VA ;

CLARKE, JU .

ENVIRONMENTAL HEALTH PERSPECTIVES, 1989, 81 :225-239

[6] METHOD FOR THE DETERMINATION OF 3 TOXIC NON-ORTHOCHLORINE SUBSTITUTED COPLANAR PCBS IN ENVIRONMENTAL-SAMPLES AT PART-PER-TRILLION LEVELS [J].

TANABE, S ;

KANNAN, N ;

WAKIMOTO, T ;

TATSUKAWA, R .

INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY, 1987, 29 (03) :199-213

[7] HIGHLY TOXIC COPLANAR PCBS - OCCURRENCE, SOURCE, PERSISTENCY AND TOXIC IMPLICATIONS TO WILDLIFE AND HUMANS [J].

TANABE, S ;

KANNAN, N ;

SUBRAMANIAN, A ;

WATANABE, S ;

TATSUKAWA, R .

ENVIRONMENTAL POLLUTION, 1987, 47 (02) :147-163

[8]

TUINSTRA LGMT, 1990, HRC-J HIGH RES CHROM, V13, P797, DOI 10.1002/jhrc.1240131202

[9] AUTOMATED CLEANUP PROCEDURE FOR THE GAS CHROMATOGRAPHIC-HIGH-RESOLUTION MASS-SPECTROMETRIC DETERMINATION OF POLYCHLORINATED DIBENZO-P-DIOXINS AND DIBENZOFURANS IN MILK [J].

VANRHIJN, JA ;

TRAAG, WA ;

KULIK, W ;

TUINSTRA, LGMT .

JOURNAL OF CHROMATOGRAPHY, 1992, 595 (1-2) :289-299

[10] ASSESSMENT OF THE TOXICITY OF MIXTURES OF HALOGENATED DIBENZO-P-DIOXINS AND DIBENZOFURANS BY USE OF TOXICITY EQUIVALENCY FACTORS (TEF) [J].

VANZORGE, JA ;

VANWIJNEN, JH ;

THEELEN, RMC ;

OLIE, K ;

VANDENBERG, M .

CHEMOSPHERE, 1989, 19 (12) :1881-1895

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