PROTEOLYTIC MATURATION OF INSULIN IS A POST-GOLGI EVENT WHICH OCCURS IN ACIDIFYING CLATHRIN-COATED SECRETORY VESICLES

被引：310

作者：

ORCI, L

RAVAZZOLA, M

STORCH, MJ

ANDERSON, RGW

VASSALLI, JD

PERRELET, A

机构：

[1] UNIV FREIBURG,MED KLIN,KLIN ENDOKRINOL ABT,D-7800 FREIBURG,FED REP GER

[2] UNIV TEXAS,HLTH SCI CTR,DEPT CELL BIOL,DALLAS,TX 75235

来源：

CELL | 1987年 / 49卷 / 06期

关键词：

D O I：

10.1016/0092-8674(87)90624-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：865 / 868

页数：4

共 12 条

[1] VISUALIZATION OF ACIDIC ORGANELLES IN INTACT-CELLS BY ELECTRON-MICROSCOPY
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[2] SPECIMEN PREPARATION FOR ELECTRON-MICROSCOPY USING LOW-TEMPERATURE EMBEDDING RESINS
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[J]. JOURNAL OF MICROSCOPY-OXFORD, 1982, 126 (APR): : 77 - 85
[3] CONVERSION OF PROINSULIN TO INSULIN - INVOLVEMENT OF A 31,500 MOLECULAR-WEIGHT THIOL PROTEASE
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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (15): : 4613 - 4617
[4] METHOD FOR ISOLATION OF INTACT ISLETS OF LANGERHANS FROM RAT PANCREAS
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[J]. DIABETES, 1967, 16 (01) : 35 - +
[5] HUMAN PROINSULIN-SPECIFIC ANTIGENIC DETERMINANTS IDENTIFIED BY MONOCLONAL-ANTIBODIES
MADSEN, OD
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STEINER, DF
[J]. DIABETES, 1984, 33 (10) : 1012 - 1016
[6] DIRECT IDENTIFICATION OF PROHORMONE CONVERSION SITE IN INSULIN-SECRETING CELLS
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MADSEN, O
VASSALLI, JD
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[J]. CELL, 1985, 42 (02) : 671 - 681
[7] CONVERSION OF PROINSULIN TO INSULIN OCCURS COORDINATELY WITH ACIDIFICATION OF MATURING SECRETORY VESICLES
ORCI, L
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AMHERDT, M
MADSEN, O
PERRELET, A
VASSALLI, JD
ANDERSON, RGW
[J]. JOURNAL OF CELL BIOLOGY, 1986, 103 (06) : 2273 - 2281
[8] BANTING LECTURE 1981 - MACRO-DOMAINS AND MICRODOMAINS IN THE ENDOCRINE PANCREAS
ORCI, L
[J]. DIABETES, 1982, 31 (06) : 538 - 565
[9] PORTRAIT OF PANCREATIC B-CELL - MINKOWSKI AWARD LECTURE DELIVERED ON JULY 19, 1973, DURING 8TH CONGRESS OF INTERNATIONAL DIABETES FEDERATION, HELD IN BRUSSELS, BELGIUM
ORCI, L
[J]. DIABETOLOGIA, 1974, 10 (03) : 163 - 187
[10] ULTRASTRUCTURAL LOCALIZATION OF INTRACELLULAR ANTIGENS BY THE USE OF PROTEIN A-GOLD COMPLEX
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[J]. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 1978, 26 (12) : 1074 - 1081

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