PREPARATION AND PERFORMANCE EVALUATION OF PLAIN PROLIPOSOMAL SYSTEMS FOR CYTOPROTECTION

被引：15

作者：

KATARE, OP

VYAS, SP

DIXIT, VK

机构：

[1] Department of Pharmaceutical Sciences, Dr H. S. Gour Vishwavidyalaya, Sagar, MP

来源：

JOURNAL OF MICROENCAPSULATION | 1991年 / 8卷 / 03期

关键词：

D O I：

10.3109/02652049109069555

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Plain liposomal systems composed of soyabean lecithin, cholesterol and stearylamine were formulated using various approaches. The prepared products were characterized and evaluated for their cytoprotective performance against the necrotizing NSAID's (i.e. aspirin and phenylbutazone). Liposomes derived from proliposomes (effervescent granules based) demonstrated the best cytoprotective activity and physical and stability characteristics. This system was shown to be superior. An increased availability of regular and small sized liposome born phospholipids to the damaged mucosal systems accounted for its better and enhanced performance.

引用

页码：295 / 300

页数：6

共 6 条

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[2]

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[6]

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