INVESTIGATIONS ON FUNGICIDES. III. THE FUNGITOXICITY OF 3-AND 5-ALKYL-SALICYLANILIDES AND PARA-CHLOROANILIDES

The anilides and para-chloroanilides have been prepared from the first four homologues of the 3- and 5-alkylsalicylic acid series and the fungistatic activity of these compounds has been assessed by two methods. In tests against mycelium, the chloroanilides usually induced less retardation of growth than the corresponding anilides. The effect of introducing an alkyl grouping was in general to reduce the fungistatic effect but with the n-propyl derivatives this trend was less marked. Salicylanilide gave the greatest over-all inhibition of the fungi investigated.