EFFECT OF TOPICAL DICLOFENAC SOLUTION ON DISCOMFORT AFTER RADIAL KERATOTOMY

被引：25

作者：

EPSTEIN, RL

LAURENCE, EP

机构：

来源：

JOURNAL OF CATARACT AND REFRACTIVE SURGERY | 1994年 / 20卷 / 04期

关键词：

DICLOFENAC; PAIN; RADIAL KERATOTOMY;

D O I：

10.1016/S0886-3350(13)80170-8

中图分类号：

R77 [眼科学];

学科分类号：

100212 [眼科学];

摘要：

The eyes of 65 consecutive radial keratotomy patients were treated topically with either diclofenac sodium 0.1% (Voltaren(R)) solution or with Tears Naturale(R) (control group) preoperatively and postoperatively in a prospective, randomized, double-masked study. During the first postoperative day, patients completed a questionnaire on discomfort level present at 15 minutes and at one, three, six, and 18 hours after surgery. Patients treated with topical diclofenac were generally more comfortable than patients in the control group. They had a significantly lower rate of ''moderate'' or ''severe'' discomfort and a higher rate of less than ''mild'' discomfort. Peak discomfort occurred at three hours in both groups. The prescribed optional oral analgesic was taken by 48.5% of patients in the diclofenac group and by 71.9% of those in the control group.

引用

页码：378 / 380

页数：3

共 8 条

[1]

Rowsey JJ, Balyeat HD, Radial keratotomy: preliminary report of complications, Ophthalmic Surg, 13, pp. 27-35, (1982)

[2]

Rashid ER, Waring GO, Complications of radial and transverse keratotomy, Surv Ophthalmol, 34, pp. 73-106, (1989)

[3]

John ME, Parrino JP, Practical hypnotic suggestion in ophthalmic surgery, Am J Ophthalmol, 96, pp. 540-542, (1983)

[4]

Eiferman RA, Hoffman RS, Sher NA, Topical diclofenac reduces pain following photorefractive keratectomy (correspondence), Arch Ophthalmol, 111, (1993)

[5]

Sher NA, Frantz JM, Talley A, Et al., Topical diclofenac in the treatment of ocular pain after excimer photorefractive keratectomy, Refract Corneal Surg, 9, pp. 425-436, (1993)

[6]

Spiers EM, Tavendale A, MacConnachie A, Beck JS, The effect of non-steroidal anti-inflammatory drugs on phytohaemagglutinin stimulated lymphocytes: relevance to possible therapeutic immunosuppression by fenclofenac, Int J Immunopharmacol, 10, pp. 261-269, (1988)

[7]

Toszoowski J, Effect of drugs inhibiting prostaglandin activity on the appearance of leukocytes in the tears after experimental injury to the corneal epithelium, Klin Oczna, 93, pp. 241-243, (1991)

[8]

Levi S, Goodlad RA, Lee CY, Et al., Non-steroidal antiinflammatory drugs inhibit the processes of mucosal cell proliferation associated with duodenal ulcer healing, Digestion, 53, pp. 129-133, (1992)

← 1 →