SPONTANEOUS CA2+ SPIKES AND WAVES IN EMBRYONIC NEURONS - SIGNALING SYSTEMS FOR DIFFERENTIATION

被引：144

作者：

SPITZER, NC ^{[1
]}

机构：

[1] UNIV CALIF SAN DIEGO, CTR MOLEC GENET, LA JOLLA, CA 92093 USA

来源：

TRENDS IN NEUROSCIENCES | 1994年 / 17卷 / 03期

关键词：

D O I：

10.1016/0166-2236(94)90120-1

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Many excitable cells are specialized to promote Ca2+ influx at early stages of development. This article focuses an spontaneous fluctuations of intracellular Ca2+ that are observed during this period. Removal of Ca2+ or suppression of influx alters subsequent differentiation. Thus these signals appear to regulate aspects of early maturation.

引用

页码：115 / 118

页数：4

共 74 条

[1] CALCIUM-DEPENDENT REGULATION OF THE ENKEPHALIN PHENOTYPE BY NEURONAL-ACTIVITY DURING EARLY ONTOGENY [J].

AGOSTON, DV ;

EIDEN, LE ;

BRENNEMAN, DE .

JOURNAL OF NEUROSCIENCE RESEARCH, 1991, 28 (01) :140-148

[2]

ASHCROFT FM, 1988, ANNU REV NEUROSCI, V11, P97, DOI 10.1146/annurev.ne.11.030188.000525

[3] REGULATION OF GENE-EXPRESSION IN HIPPOCAMPAL-NEURONS BY DISTINCT CALCIUM SIGNALING PATHWAYS [J].

BADING, H ;

GINTY, DD ;

GREENBERG, ME .

SCIENCE, 1993, 260 (5105) :181-186

[4] INCREASES IN INTRACELLULAR CALCIUM-ION CONCENTRATION DURING DEPOLARIZATION OF CULTURED EMBRYONIC XENOPUS SPINAL NEURONS [J].

BARISH, ME .

JOURNAL OF PHYSIOLOGY-LONDON, 1991, 444 :545-565

[5] SPATIAL AND TEMPORAL ASPECTS OF CELL SIGNALING [J].

BERRIDGE, MJ ;

COBBOLD, PH ;

CUTHBERTSON, KSR .

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES, 1988, 320 (1199) :325-343

[6] INTRANUCLEAR CA2+ TRANSIENTS DURING NEURITE REGENERATION OF AN ADULT MAMMALIAN NEURON [J].

BIRCH, BD ;

ENG, DL ;

KOCSIS, JD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (17) :7978-7982

[7] EARLY DIFFERENTIATION OF VERTEBRATE SPINAL NEURONS IN THE ABSENCE OF VOLTAGE-DEPENDENT CA-2+ AND NA+ INFLUX [J].

BIXBY, JL ;

SPITZER, NC .

DEVELOPMENTAL BIOLOGY, 1984, 106 (01) :89-96

[8] THE APPEARANCE AND DEVELOPMENT OF CHEMOSENSITIVITY IN ROHON-BEARD NEURONS OF THE XENOPUS SPINAL-CORD [J].

BIXBY, JL ;

SPITZER, NC .

JOURNAL OF PHYSIOLOGY-LONDON, 1982, 330 (SEP) :513-536

[9]

BLANTON MG, 1991, J NEUROSCI, V11, P3907

[10] INTERCELLULAR SIGNALING IN GLIAL-CELLS - CALCIUM WAVES AND OSCILLATIONS IN RESPONSE TO MECHANICAL STIMULATION AND GLUTAMATE [J].

CHARLES, AC ;

MERRILL, JE ;

DIRKSEN, ER ;

SANDERSON, MJ .

NEURON, 1991, 6 (06) :983-992

← 1 2 3 4 5 6 7 8 →