ANALYZING SURVIVAL IN THE PRESENCE OF AN AUXILIARY VARIABLE

被引:42
作者
FINKELSTEIN, DM [1 ]
SCHOENFELD, DA [1 ]
机构
[1] MASSACHUSETTS GEN HOSP,BOSTON,MA 02114
关键词
D O I
10.1002/sim.4780131706
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
A primary endpoint of AIDS trials is the length of survival. Often there is auxiliary information available on measures of disease progression, which significantly alter the risk of mortality. This paper explores the use of this information in obtaining a refined estimate of survival, and a test based on this estimate. The methods are applied to an AIDS clinical trial, and results of simulations are provided which compare the approach to standard methods for survival analysis.
引用
收藏
页码:1747 / 1754
页数:8
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