TRANSCRIPTIONAL SILENCING AND THERMOREGULATION OF GENE-EXPRESSION IN ESCHERICHIA-COLI

被引：264

作者：

GORANSSON, M ^{[1
]}

SONDEN, B ^{[1
]}

NILSSON, P ^{[1
]}

DAGBERG, B ^{[1
]}

FORSMAN, K ^{[1
]}

EMANUELSSON, K ^{[1
]}

UHLIN, BE ^{[1
]}

机构：

[1] UMEA UNIV,DEPT MICROBIOL,S-90187 UMEA,SWEDEN

来源：

NATURE | 1990年 / 344卷 / 6267期

关键词：

D O I：

10.1038/344682a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

EXPRESSION of specific adhesive properties by bacteria in general seems to be regulated to fit the environmental conditions. An example is the transcriptional regulation of digalactoside-specific binding by uropathogenic strains of Escherichia coli1. The fimbrial structures (pili) on the bacterial surface carry the adhesin and are present during growth at 37 °C but are not produced by cells at lower temperatures, such as 25 °C. Thermoregulation of expression is due to temperature-dependent transcription of a regulatory cistron in the pilus-adhesin gene cluster. We have now identified and characterized a new regulatory locus (drdX) and show that a histone-like bacterial protein has an important role in this novel example of thermoregulation of transcription. © 1990 Nature Publishing Group.

引用

页码：682 / 685

页数：4

共 30 条

[1] TRANSCRIPTIONAL ACTIVATION OF A PAP PILUS VIRULENCE OPERON FROM UROPATHOGENIC ESCHERICHIA-COLI [J].