CARBOCYCLES FROM CARBOHYDRATES - A FREE-RADICAL ROUTE TO (1R,2R,3S,4R)-4-AMINO-1,2,3-CYCLOPENTANETRIOL DERIVATIVES

Some derivatives of (1R, 2R, 3S, 4R)-4-amino-1,2,3-cyclopentanetriol have been synthesized in enantiomerically pure form via free radical cyclization of conveniently functionalized carbohydrate intermediates. Moderate yields and good to excellent diastereoselectivities have been obtained in the key intramolecular free radical cyclization step.