Adrenomedullin-immunoreactive neurons in the paraventricular and supraoptic nuclei of the rat

被引:98
作者
Ueta, Y
Kitamura, K
Isse, T
Shibuya, I
Kabashima, N
Yamamoto, S
Kangawa, K
Matsuo, H
Eto, T
Yamashita, H
机构
[1] UNIV OCCUPAT & ENVIRONM HLTH, SCH MED, DEPT PHYSIOL, YAHATANISHI KU, KITAKYUSHU, FUKUOKA 807, JAPAN
[2] MIYAZAKI MED COLL, DEPT INTERNAL MED 1, MIYAZAKI 88916, JAPAN
[3] NATL CARDIOVASC CTR, RES INST, SUITA, OSAKA 565, JAPAN
关键词
adrenomedullin; paraventricular nucleus; supraoptic nucleus; vasopressin; oxytocin; rat;
D O I
10.1016/0304-3940(95)12204-4
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The existence of adrenomedullin (AM) in the rat hypothalamus was examined by immunohistochemistry. AM-immunoreactive neurons were found in the supraoptic nucleus (SON) and in the magnocellular parts of the paraventricular nucleus (PVN). The co-existence of AM-, oxytocin- and/or vasopressin-immunoreactivity was identified in the same neurons in the hypothalamus. The results suggest that the AM may play a role in neurotransmission or in cardiovascular control with neurohypophyseal hormones.
引用
收藏
页码:37 / 40
页数:4
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