A THEORETICAL APPROACH TO DESCRIBE MONOLAYER-LIPOSOME LIPID INTERACTION

被引：18

作者：

HERNANDEZBORRELL, J

MAS, F

PUY, J

机构：

[1] UNIV POLITECN CATALUNYA,ESCOLA TECN SUPER ENGN AGR,CHEM SECT,CATALUNYA,SPAIN

[2] UNIV BARCELONA,FAC QUIM,DEPT PHYS CHEM,E-08028 BARCELONA,SPAIN

来源：

BIOPHYSICAL CHEMISTRY | 1990年 / 36卷 / 01期

关键词：

Lipid interaction; Liposome; Monolayer; Theoretical model;

D O I：

10.1016/0301-4622(90)85006-R

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

It is known from several studies on the interaction between membrane models that mechanisms such as fusion or lipid exchange can play an important role in the process of internalization by cells of lipid vesicles and also in the physical stability of liposomes. In this paper it is shown that a simple monolayer-liposome model can be used to simulate experimentally observed interactions between lipid vesicles and cell surfaces. From experimental data, a simple theoretical model is formulated to interpret the variation with time of surface pressure as a function of liposome concentration. The congruency of the physico-chemical hypothesis and its validity are studied and correlated with results from experimental systems. © 1990.

引用

页码：47 / 55

页数：9

共 31 条

[1]

ADAMSON AW, 1982, PHYSICAL CHEM SURFAC

[2] INTERACTION BETWEEN CA-2+ AND DIPALMITOYLPHOSPHATIDYLCHOLINE MEMBRANES .1. TRANSITION ANOMALIES OF ULTRASONIC PROPERTIES [J].