UNNATURAL ALKALOIDS

被引：4

作者：

BROSSI, A

机构：

[1] Medicinal Chemistry Section, Laboratory of Chemistry, National Institute of Arthritis, Metabolism and Digestive Diseases, National Institutes of Health, Bethesda, Maryland

来源：

PURE AND APPLIED CHEMISTRY | 1979年 / 51卷 / 04期

关键词：

D O I：

10.1351/pac197951040681

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

There are many good reasons for synthesizing and studying unnatural relatives of biologically active natural products particularly alkaloids. Such “unnatural” substances may include optical isomers, deoxy-congeners, dimers and metabolites from mammalian and human tissue, related, but not identical, to plant alkaloids. The chemistry and biological behavior of such “unnatural” alkaloids is presented. © IUPAC

引用

页码：681 / 688

页数：8

共 29 条

[1] PRESENT STATUS OF MALARIA CHEMOTHERAPY [J].

BROSSI, A .

HETEROCYCLES, 1976, 5 :631-647

[2]

COLLINS AC, 1974, J CHROMATOGR, V99, P567

[3] HERSTELLUNG DES RACEMISCHEN COLCHICINS UND DES UNNATURLICHEN (+)-COLCHICINS [J].

CORRODI, H ;

HARDEGGER, E .

HELVETICA CHIMICA ACTA, 1957, 40 (01) :193-199

[4] PAVINANE AND ISOPAVINANE ALKALOIDS - CORRELATION OF ABSOLUTE-CONFIGURATIONS BY SYNTHESIS [J].

DYKE, SF ;

KINSMAN, RG ;

WARREN, P ;

WHITE, AWC .

TETRAHEDRON, 1978, 34 (02) :241-245

[5]

EDDY NB, 1973, SCIENCE, V192, P410

[6] CLOSURE OF OXIDE BRIDGE IN MORPHINE SERIES [J].

GATES, M ;

SHEPARD, MS .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1962, 84 (21) :4125-&

[7]

Goto K., 1964, SINOMENINE OPTICAL A

[8]

GOTO K, 1949, B CHEM SOC JPN, V22, P262

[9] STUDIES IN (+)-MORPHINAN SERIES .4. MARKEDLY IMPROVED SYNTHESIS OF (+)-MORPHINE [J].

IIJIMA, I ;

MINAMIKAWA, JI ;

JACOBSON, AE ;

BROSSI, A ;

RICE, KC .

JOURNAL OF ORGANIC CHEMISTRY, 1978, 43 (07) :1462-1463

[10] STUDIES IN (+)-MORPHINAN SERIES .5. SYNTHESIS AND BIOLOGICAL PROPERTIES OF (+)-NALOXONE [J].

IIJIMA, I ;

MINAMIKAWA, J ;

JACOBSON, AE ;

BROSSI, A ;

RICE, KC ;

KLEE, WA .

JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (04) :398-400

← 1 2 3 →