TIN(II) CHLORIDE DIHYDRATE - A MILD AND EFFICIENT REAGENT FOR CLEAVING ACETALS

被引：33

作者：

FORD, KL ^{[1
]}

ROSKAMP, EJ ^{[1
]}

机构：

[1] NORTHWESTERN UNIV,DEPT CHEM,EVANSTON,IL 60208

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 09期

关键词：

TIN(II) CHLORIDE DIHYDRATE; LEWIS ACID; DEPROTECTION OF ACETALS;

D O I：

10.1016/S0040-4039(00)91878-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Tin(II) chloride dihydrate (SnCl2.2H2O) efficiently converts conjugated dioxolanes, and both dimethoxy and diethoxy acetals to aldehydes (84-98%). Similarly, nonconjugated dimethoxy and diethoxy acetals are also efficiently converted to aldehydes (84-94%). Conjugated pyrans and nonconjugated dioxolanes, however, are only converted to aldehydes in 17-38% yields.

引用

页码：1135 / 1138

页数：4

共 18 条

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