STEREOCONTROLLED SYNTHESIS OF (-)-ALLOSAMIZOLINE USING D-GLUCOSAMINE AS A CHIRAL TEMPLATE

被引：37

作者：

TAKAHASHI, S ^{[1
]}

TERAYAMA, H ^{[1
]}

KUZUHARA, H ^{[1
]}

机构：

[1] RIKEN,INST PHYS & CHEM RES,WAKO,SAITAMA 35101,JAPAN

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 38期

关键词：

(-)-ALLOSAMIZOLINE; INSECT CHITINASE INHIBITOR; ALLOSAMIDIN; D-GLUCOSAMINE; RING CONTRACTION REACTION;

D O I：

10.1016/S0040-4039(00)93444-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(-)-Allosamizoline (1), a core component of novel insect chitinase inhibitor, allosamidin (2), was stereoselectively synthesized from D-glucosamine (3), using an efficient ring contraction reaction as a key step.

引用

页码：5123 / 5126

页数：4

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