INSOMNIA FOLLOWING PARACHLOROPHENYLALANIN IN RAT

被引：133

作者：

MOURET, J

BOBILLIER, P

JOUVET, M

机构：

[1] Laboratoire de Pathologie Expérimentale, Faculté de Médecine, Lyon

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY | 1968年 / 5卷 / 01期

关键词：

5-HT synthesis; NA-DA slow wave sleep; p-chlorophenylalanin; paradoxical sleep; Rat brain; Sleep states; Synthesis-inhibition;

D O I：

10.1016/0014-2999(68)90151-9

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Intraperitoneal injection of 500 mg/kg of parachlorophenylalanin is followed by a significant decrease of both slow wave sleep and paradoxical sleep in the rat (as measured by continuous polygraphic recordings). There is a significant correlation between the decrease of cerebral serotonin, the decrease of slow wave sleep and the decrease of the rate of occurrence of paradoxical sleep. © 1993.

引用

页码：17 / +

页数：1

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