METABOLISM OF IMMUNOGLOBULIN-A, LYMPHOCYTE FUNCTION, AND HISTOCOMPATIBILITY ANTIGENS IN PATIENTS ON ANTICONVULSANTS

被引：45

作者：

SHAKIR, RA ^{[1
]}

BEHAN, PO ^{[1
]}

DICK, H ^{[1
]}

LAMBIE, DG ^{[1
]}

机构：

[1] GLASGOW ROYAL INFIRM,DEPT BACTERIOL,TISSUE TYPING LAB,GLASGOW G4 0SF,SCOTLAND

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1978年 / 41卷 / 04期

关键词：

D O I：

10.1136/jnnp.41.4.307

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Low serum IgA levels were found in patients taking phenytoin, together with evidence of depressed T cell function. There was no correlation between the dose or the serum level. A correlation was found, however, with HL-A status, patients with a low IgA showing increased frequency of HL-A2. It is suggested that epileptic patients with HL-A2 status are likely to develop IgA deficiency when given phenytoin.

引用

页码：307 / 311

页数：5

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