SIGNIFICANCE OF MIGRATION STIMULATORY FACTOR IN HUMAN RENAL ALLOTRANSPLANTATION

被引：3

作者：

CERILLI, J

FESPERMAN, DP

机构：

[1] Department of Surgery, Ohio State University, College of Medicine, Columbus, OH

来源：

TRANSPLANTATION | 1979年 / 27卷 / 04期

关键词：

D O I：

10.1097/00007890-197904000-00015

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Seventy-four recipients of related donor renal allografts were tested for the presence of cellular immunity to specific donor lymphocyte antigens using the direct migration inhibition factor (MIF) assay. Responses on the assay fell into one of the following three statistically distinct groups: (1) greater than 20% inhibition of macrophage migration, (2) nonresponsiveness, 10% of control migration, and (3) greater than 12% stimulation of macrophage migration. Migration stimulation was shown to be reproducible and to correlate well with a very benign post-transplant clinical course. The production of migration stimulatory factor appears to be an immunological response analagous to the production of migration inhibition factor. © 1979 by The Williams … Wilkins Co.

引用

页码：279 / 282

页数：4

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