PROLACTIN-SECRETING PITUITARY-ADENOMA IN A MAN WITH GIGANTISM - CASE-REPORT

被引：2

作者：

PEILLON, F ^{[1
]}

PHILIPPON, J ^{[1
]}

BRANDI, AM ^{[1
]}

FOHANNO, D ^{[1
]}

LAPLANE, D ^{[1
]}

DUBOIS, MP ^{[1
]}

DECOURT, J ^{[1
]}

机构：

[1] CTR HOSP UNIV PITIE SALPETRIERE,MALAD SYST NERVEUX CLIN,F-75634 PARIS 13,FRANCE

来源：

ACTA ENDOCRINOLOGICA | 1979年 / 92卷 / 04期

关键词：

D O I：

10.1530/acta.0.0920627

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A prolactin-secreting pituitary adenoma was removed trans-sphenoidally from a 37 years old man with gigantism (218 cm). Serum levels of prolactin (PRL) were elevated pre-operatively and decreased after administration of L-Dopa with no increase after TRH as is usually observed in PRL-secreting adenomas. Growth hormone (GH) and somatomedin serum levels were normal with no modification of GH after insulin hypoglycaemia, oral glucose loading or L-Dopa. Morphological examination of the tumour demonstrated the presence of lactotrophs by light and electron microscopy and by immunofluorescense staining. No somatotrophs were found. In this unique case, the relationship between a PRL-secreting adenoma and gigantism is discussed.

引用

页码：627 / 639

页数：13

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