ANTIOXIDANT ACTION OF PROPOFOL ON LIVER-MICROSOMES, MITOCHONDRIA AND BRAIN SYNAPTOSOMES IN THE RAT

被引：76

作者：

MUSACCHIO, E

RIZZOLI, V

BIANCHI, M

BINDOLI, A

GALZIGNA, L

机构：

[1] Department of Biological Chemistry, University of Padova, Padova, 35121

来源：

PHARMACOLOGY & TOXICOLOGY | 1991年 / 69卷 / 01期

关键词：

D O I：

10.1111/j.1600-0773.1991.tb00414.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

2,6-Diisopropylphenol (propofol), a new intravenous anaesthetic, has a structure similar to that of butylated hydroxytoluene (BHT). Both compounds inhibit the production of malondialdehyde (MDA) in rat liver mitochondria and microsomes as well as in rat brain synaptosomes treated with lipid peroxidation inducers.

引用

页码：75 / 77

页数：3

共 15 条

[1]

BIANCHI M, 1991, IN PRESS NEUROCHEM R, V16

[2] ANTIOXIDANT ACTION AND PHOTOSENSITIZING EFFECTS OF 3 DIFFERENT CHLORPROMAZINES [J].