INFLUENCE OF SPINAL-CORD TRANSECTION ON SPINAL-CORD BLOOD-FLOW IN RATS

被引：6

作者：

TURNER, J ^{[1
]}

HEAVNER, JE ^{[1
]}

机构：

[1] UNIV WASHINGTON,ANESTHESIA RES CTR,SEATTLE,WA 98195

来源：

GENERAL PHARMACOLOGY | 1978年 / 9卷 / 06期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0306-3623(78)90036-8

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

1. 1. [14C] antipyrine accumulation in the spinal cord lumbosacral enlargement of rats with cervical or thoracolumbar cord transection and its accumulation in the enlargement of normotensive and hypotensive rats without cord transection was compared. 2. 2. Overall, the pattern of antipyrine rise and fall in the first 15 min interval after intravenous injection of the compound was similar in all four groups of animals. 3. 3. The results indicate that spinal cord blood flow is qualitatively similar under the experimental conditions studied and thus drugs having physiochemical properties similar to antipyrine would be similarly distributed in the different preparations investigated. © 1978.

引用

页码：463 / 465

页数：3

共 10 条

[1]

BRODIE BB, 1950, J PHARMACOL EXP THER, V98, P97

[2] ANATOMICAL OBSERVATIONS ON ARTERIAL SUPPLY TO LUMBOSACRAL SPINAL-CORD OF CAT [J].