POLYMORPHISMS OF ALPHA-1-ACID (OROSOMUCOID), ALPHA-2-HS-GLYCOPROTEINS AND ALPHA-1-B AMONG THE PARSIS OF INDIA

被引：9

作者：

SAHA, N

UNDEVIA, JV

JUNEJA, RK

GAHNE, B

TAY, JSH

机构：

[1] CANC RES INST,TATA MEM CTR,BOMBAY 400012,INDIA

[2] SWEDISH UNIV AGR SCI,DEPT ANIM BREEDING & GENET,S-75007 UPPSALA,SWEDEN

来源：

HUMAN HEREDITY | 1992年 / 42卷 / 06期

关键词：

ZOROASTRIAN PARSIS; BOMBAY; PLASMA PROTEINS; POLYMORPHISMS; OROSOMUCOID; ISOELECTRIC FOCUSING; IMMUNOBLOTTING; 2-D ELECTROPHORESIS; POPULATION GENETICS;

D O I：

10.1159/000154099

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Genetic polymorphisms of plasma alpha1-acid glycoprotein (orosomucoid, ORM), alpha2-HS-glycoprotein (A2HS) and alpha1-B-glycoprotein (alpha1B) were studied in a group of Parsis in Bombay, India. The frequencies of ORM1*1, ORM1*2 and ORM1*3 were found to be 0.636, 0.356 and 0.008, respectively. A2HS*1, A2HS*2 and A2HS*3 frequencies were 0.855, 0.135 and 0.010, while the frequencies of A1B*1 and A1B*2 were 0.881 and 0.119, respectively. The phenotype distribution at all three loci was at Hardy-Weinberg equilibrium. The ORM2 locus was monomorphic in the Parsis.

引用

页码：367 / 371

页数：5

共 22 条

[1]

ABE S, 1986, JPN J HUM GENET, V31, P187

[2]

BOUTIN B, 1985, AM J HUM GENET, V37, P1098

[3]

COX DW, 1983, ELECTROPHORESIS 82, P243

[4]

ESCALLON MH, 1987, AM J HUM GENET, V41, P418