IMMUNOELECTRONMICROSCOPIC QUANTITATION OF DIFFERENTIAL LEVELS OF CHLAMYDIAL PROTEINS IN A CELL-CULTURE MODEL OF PERSISTENT CHLAMYDIA-TRACHOMATIS INFECTION

被引:48
作者
BEATTY, WL
MORRISON, RP
BYRNE, GI
机构
[1] UNIV WISCONSIN,DEPT MED MICROBIOL & IMMUNOL,MADISON,WI 53706
[2] NIAID,ROCKY MT LABS,INTRACELLULAR PARASITES LAB,HAMILTON,MT 59840
关键词
D O I
10.1128/IAI.62.9.4059-4062.1994
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Electron immunolabeling techniques were used for quantitative evaluation of alterations in the steady-state levels of chlamydial antigens in persistent Chlamydia trachomatis cultures. Gamma interferon-mediated persistent chlamydial development correlated with an increase in the levels of the chlamydial heat shock protein (hsp60) and with a significant reduction in the levels of the major outer membrane protein.
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页码:4059 / 4062
页数:4
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