ZINC FINGERS

被引：133

作者：

RHODES, D

KLUG, A

机构：

[1] Medical Research Council Laboratory of Molecular Biology, Cambridge

来源：

SCIENTIFIC AMERICAN | 1993年 / 268卷 / 02期

关键词：

D O I：

10.1038/scientificamerican0293-56

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

These projections on transcription factors grip specific sites on DNA, preparing genes for activation. Since they were discovered in 1985, proteins incorporating zinc fingers have been identified in diverse species, from yeast to humans. Several laboratories have begun to decipher how these zinc-containing proteins select and bind to DNA and to elucidate the role they play in switching on genes.

引用

页码：56 / &

共 6 条

[1] A STRUCTURAL TAXONOMY OF DNA-BINDING DOMAINS [J].