5-FLUOROURACIL-METHOTREXATE SYNERGY - ENHANCEMENT OF 5-FLUORODEOXYURIDYLATE BINDING TO THYMIDYLATE SYNTHASE BY DIHYDROPTEROYLPOLYGLUTAMATES

被引：74

作者：

FERNANDES, DJ ^{[1
]}

BERTINO, JR ^{[1
]}

机构：

[1] YALE UNIV,SCH MED,DEPT MED,NEW HAVEN,CT 06510

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES | 1980年 / 77卷 / 10期

关键词：

D O I：

10.1073/pnas.77.10.5663

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：5663 / 5667

页数：5

共 42 条

[1] POLYGAMMAGLUTAMYL METABOLITES OF METHOTREXATE [J].

BAUGH, CM ;

KRUMDIECK, CL ;

NAIR, MG .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1973, 52 (01) :27-34

[2]

BERTINO JR, 1977, CANCER RES, V37, P327

[3] INTERCONVERSION OF SERINE AND GLYCINE - PREPARATION AND PROPERTIES OF CATALYTIC DERIVATIVES OF PTEROYLGLUTAMIC ACID [J].

BLAKLEY, RL .

BIOCHEMICAL JOURNAL, 1957, 65 (02) :331-342

[4]

BLAKLEY RL, 1969, FRONTIERS BIOL, P118

[5]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[6] THERAPEUTIC CONSEQUENCES OF ANTITUMOUR DRUG INTERACTIONS - METHOTREXATE AND 5-FLUOROURACIL IN CHEMOTHERAPY OF C3H MICE WITH TRANSPLANTED MAMMARY ADENOCARCINOMA [J].

BROWN, I ;

WARD, HWC .

CANCER LETTERS, 1978, 5 (05) :291-297

[7] ENHANCED 5-FLUOROURACIL NUCLEOTIDE FORMATION AFTER METHOTREXATE ADMINISTRATION - EXPLANATION FOR DRUG SYNERGISM [J].

CADMAN, E ;

HEIMER, R ;

DAVIS, L .

SCIENCE, 1979, 205 (4411) :1135-1137

[8]

Cashmore A R, 1980, Methods Enzymol, V66, P459

[9]

CHU MY, 1968, BIOCHEM PHARMACOL, V17, P753

[10] 7,8-DIHYDROPTEROYL OLIGO-GAMMA-L-GLUTAMATES - SYNTHESIS AND KINETIC STUDIES WITH PURIFIED DIHYDROFOLATE-REDUCTASE FROM MAMMALIAN SOURCES [J].

COWARD, JK ;

PARAMESWARAN, KN ;

CASHMORE, AR ;

BERTINO, JR .

BIOCHEMISTRY, 1974, 13 (19) :3899-3903

← 1 2 3 4 5 →