PKC-ZETA;
CDNA CLONING;
RAT;
MOUSE;
GENE FAMILY;
HUMAN BRAIN;
SIGNAL TRANSDUCTION;
D O I:
10.1016/0378-1119(93)90213-M
中图分类号:
Q3 [遗传学];
学科分类号:
071007 ;
090102 ;
摘要:
A 1779-bp complementary DNA (cDNA) that encodes protein kinase C-zeta (PKC-zeta) has been isolated from a human frontal cortex library using traditional plaque-screening methods and PCR screening. The deduced 592-amino-acid sequence of the human PKC-zeta clone has a 95-96% identity to those deduced from the previously described rat and mouse PKC-zeta clones.