IN VITRO BINDING OF SALICYLATES TO SALIVA PROTEINS

被引：14

作者：

LANGE, WE

FLORIDDIA, DG

PRUYN, FJ

机构：

[1] Department of Pharmacy, Massachusetts College of Pharmacy, Boston, Massachusetts

[2] Purdue Frederick Co, Yonkers, New York

[3] College of Pharmacy, Northeastern University, Boston, Massachusetts

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1969年 / 58卷 / 06期

关键词：

Fluorometry—analysis; Salicylate binding—saliva proteins; Saliva proteins—ninhydrin test;

D O I：

10.1002/jps.2600580632

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A method has been developed whereby the in vitro binding of salicylic acid, acetylsalicylic acid, and salicylamide to saliva proteins, may be easily determined. It was found, using gel filtration, that salicylates added to saliva are bound to the saliva proteins to the extent of from 35 to 50% after a contact time of from 0.5 to 2.0 hr. at 37°. Copyright © 1969 Wiley‐Liss, Inc., A Wiley Company

引用

页码：771 / +

页数：1

共 12 条

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