LIFETIME ALCOHOL INTAKE AND RISK OF RECTAL-CANCER IN WESTERN NEW-YORK

被引:26
作者
FREUDENHEIM, JL
GRAHAM, S
MARSHALL, JR
HAUGHEY, BP
WILKINSON, G
机构
[1] Department of Social and Preventive Medicine, State University of New York, Buffalo
[2] Epidemiological Resources, Chestnut Hill
来源
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL | 1990年 / 13卷 / 1-2期
关键词
D O I
10.1080/01635589009514050
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The lifetime intake of total alcohol, beer, wine, and hard liquor was measured for 277 males and 145 females with pathologically confirmed, first, single, primary cancers of the rectum in western New York from 1978 to 1986. Controls who were age, sex, and neighborhood matched were also interviewed. Intake of beer and total alcohol was positively associated with rectal cancer risk. Most of the excess risk was found for the heaviest drinkers. Odds ratios for fourth quartile intakes for males were 1.80 (95% Cl, 1.12, 2.89) for total alcohol and 1.86 (1.13, 3.06) for beer. No association was found with wine or hard liquor intake. Females drank considerably less in this population; trends were similar although not of as great magnitude as those for males. Adjustment for dietary risk factors did not change risk estimates appreciably. A high lifetime intake of beer and total alcohol was associated with an increased risk of rectal cancer, and this was independent of either socioeconomic status or diet. © 1990, Taylor & Francis Group, LLC. All rights reserved.
引用
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页码:101 / 109
页数:9
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