PERSISTENCE OF ANTIBODIES AFTER IMMUNIZATION WITH A RECOMBINANT YEAST-DERIVED HEPATITIS-B VACCINE FOLLOWING 2 DIFFERENT SCHEDULES

被引：32

作者：

SCHEIERMANN, N ^{[1
]}

GESEMANN, M ^{[1
]}

MAURER, C ^{[1
]}

JUST, M ^{[1
]}

BERGER, R ^{[1
]}

机构：

[1] UNIV BASEL,CHILDRENS HOSP,BASEL,SWITZERLAND

来源：

VACCINE | 1990年 / 8卷

关键词：

antibody persistence; Hepatitis B; recombinant DNA;

D O I：

10.1016/0264-410X(90)90217-A

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Four years after vaccination of health adults with either a recombinant yeast-derived (YDV) or plasma-derived (PDV) hepatitis B vaccine, the persistence of antibodies to hepatitis B surface antigen (anti-HBs) was examined. Subjects received three 20 μg doses in the deltoid region according to either a 0, 1, 6 month vaccination schedule, with a 20 μg booster dose of YDV administered at month 12 for subjects on the second schedule. The recombinant vaccine was found to be immunologically comparable to the PDV, with anti-HBs persisting equally in both groups. © 1990.

引用

页码：S44 / S46

页数：3