SOLID-LIQUID PHASE-TRANSFER CATALYSIS .1. STUDIES OF THE N-ALKYLATION OF PURINES AND PYRIMIDINES

被引：28

作者：

LAZREK, HB

TAOURIRTE, M

BARASCUT, JL

IMBACH, JL

机构：

[1] Laboratoire de Chimie Bio-Organique, Faculté des Sciences de Marrakech

[2] Laboratoire de Chimie Bio-Organique, Universite de Montpellier II Sciences et Techniques du Languedoc, 34095, Montpellier Cedex 5

来源：

NUCLEOSIDES & NUCLEOTIDES | 1991年 / 10卷 / 06期

关键词：

D O I：

10.1080/07328319108047062

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

N-alkylation with acyclic side chains of pyrimidine and purine heterocycles occurs regioselectively at N-1 and N-9 respectively under solid-liquid phase transfer catalysis by 18-crown-6 or tetraglyme in the presence of potassium tert-butoxide at 0-degrees-C.

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页码：1285 / 1293

页数：9

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