CHANGES IN THE ELASTIC TISSUE OF THE NON-SUN-EXPOSED SKIN OF CIGARETTE SMOKERS

被引：58

作者：

FRANCES, C

BOISNIC, S

HARTMANN, DJ

DAUTZENBERG, B

BRANCHET, MC

LECHARPENTIER, Y

ROBERT, L

机构：

[1] HOP PITIE, DEPT HISTOPATHOL, F-75651 PARIS 13, FRANCE

[2] INST PASTEUR, CTR RADIOL, LYON, FRANCE

[3] UNIV PARIS 12, CONNECT TISSUE RES LAB, F-94010 CRETEIL, FRANCE

来源：

BRITISH JOURNAL OF DERMATOLOGY | 1991年 / 125卷 / 01期

关键词：

D O I：

10.1111/j.1365-2133.1991.tb06037.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Biopsies were taken from the upper and inner arm of 10 60-year-old male cigarette smokers and compared with 10 age-matched controls who were non-smokers. The mean relative area, number and thickness of the elastic fibres were significantly increased in the cigarette smokers compared to the controls. These results were confirmed using antibodies to elastin or the microfibrillar component of clastic tissue. In the smokers the broader and more fragmented elastic fibres in the skin were not as intensely stained as those of the non-smokers and the ultrastructural alterations of the elastic fibres were similar to those in solar elastosis.

引用

页码：43 / 47

页数：5

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