COGNITIVE-FUNCTIONING AND SCHOOL PERFORMANCE IN CHILDREN WITH RENAL-FAILURE

被引：61

作者：

LAWRY, KW

BROUHARD, BH

CUNNINGHAM, RJ

机构：

[1] Department of Pediatrics, The Cleveland Clinic Foundation, Cleveland, 44195, Ohio

[2] Department of Social Service, The Cleveland Clinic Foundation, Cleveland, 44195, Ohio

[3] Department of Nephrology and Hypertension, The Cleveland Clinic Foundation, Cleveland, 44195, Ohio

[4] Department of Cardiovascular Biology, The Cleveland Clinic Foundation, Cleveland, 44195, Ohio

[5] The Research Institute, The Cleveland Clinic Foundation, Cleveland, 44195, Ohio

来源：

PEDIATRIC NEPHROLOGY | 1994年 / 8卷 / 03期

关键词：

CHRONIC RENAL FAILURE; COGNITIVE FUNCTIONING;

D O I：

10.1007/BF00866349

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Although previous studies have documented neuropsychological deficits in children with end-stage renal disease, few have evaluated and compared the cognitive functioning and the school performance of children with renal failure. The current study evaluated the influence of chronic renal failure on cognitive functioning and school performance in children and adolescents with end-stage renal disease undergoing dialysis and after renal transplantation. Participants were given standardized IQ and achievement tests to assess cognitive functioning and ability. Academic performance was determined by evaluating grades for the semester in which the testing was performed; a grade point average (GPA) was calculated based on a 4.0-point scale. The 11 dialysis patients and 13 transplant patients were comparable in age, race, sex, and socioeconomic status. Overall IQ and subtest scores demonstrated no differences between the two groups. Performance on the Woodcock-Johnson achievement tests showed that the transplant patients did better on achievement tests of written language (P = 0.04) and in school performance in English compared with dialysis patients (P <0.05). Furthermore the dialysis patients tended to be below age and grade level in all areas, whereas the transplant patients were achieving at or above these levels. There were significant differences in the age equivalent scores between the dialysis and transplant patients in the areas of mathematics and written language (P <0.05). However, when grades were evaluated there were no differences in overall GPA or in the mathematics GPA. Days absent were not different between the two groups. These data demonstrate that both groups of patients were of similar intellectual ability; the achievement of the dialysis patients was behind that of the transplant patients and this lag was not necessarily reflected in school grades. Patients with chronic renal failure should have cognitive and achievement testing on a regular basis, and areas of deficit should be addressed by the schools.

引用

页码：326 / 329

页数：4

共 21 条

[1]

Rutter M., Tizzard J., Whitmore K., Education, health and behavior, (1970)

[2]

Davis I.D., Chang P.N., Nevins T.E., Successful renal transplantation accelerates development in young uremic children, Pediatrics, 86, pp. 591-600, (1990)

[3]

Bock G.H., Conners K., Ruley J., Samango-Sprouse C.A., Conry J.A., Weiss I., Eng G., Johnson E., David C.T., Disturbances of brain maturation and neurodevelopment during chronic renal failure in infancy, J Pediatr, 144, pp. 231-238, (1989)

[4]

Trompter R.S., Polinsky, Andreoli S.A., Fennell R.S., Neurologic complications of renal failure, American Journal of Kidney Diseases, 7, pp. 318-322, (1986)

[5]

Fennell R.S., Fennell E.B., Carter R.L., Mengs E.L., Klauser A.B., Hurst J.R., A longitudinal study of the cognitive function of children with renal failure, Pediatr Nephrol, 4, pp. 11-14, (1990)

[6]

Fennell R., Fennell E., Randolph L., Mings E., Klausner A., Hurst J., Association between renal function and cognition in childhood chronic renal failure, Pediatr Nephrol, 4, pp. 16-20, (1990)

[7]

Hobbs S.A., Sexson S.B., Cognitive development and learning in the pediatric organ transplant recipient, J Learn Disabilities, 26, pp. 104-113, (1993)

[8]

So S.K.S., Chnag P., Najarian J.S., Mauer S.M., Simmons R.L., Nevins T.E., Growth and development in infants after renal transplantation, J Pediatr, 110, pp. 343-350, (1987)

[9]

Rasbury W., Fennell R., Morris M., Cognitive functioning of children with end-stage renal disease before and after successful transplantation, J Pediatr, 102, pp. 589-592, (1983)

[10]

Fennell R.S., Rasbury W.C., Fennell E.B., Morris M.K., The effects of kidney transplantation on cognitive performance in a pediatric population, Pediatrics, 74, pp. 273-278, (1984)

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