COSEGREGATION OF HYPERTROPHIC CARDIOMYOPATHY AND A FRAGILE SITE ON CHROMOSOME-16 IN A LARGE ITALIAN FAMILY

被引：14

作者：

FERRARO, M ^{[1
]}

SCARTON, G ^{[1
]}

AMBROSINI, M ^{[1
]}

机构：

[1] UNIV ROME LA SAPIENZA,IST CHIRURG CUORE,CATTEDRA CARDIOL 2,I-00185 ROME,ITALY

来源：

JOURNAL OF MEDICAL GENETICS | 1990年 / 27卷 / 06期

关键词：

D O I：

10.1136/jmg.27.6.363

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We studied the karyotypes of 10 members of a family in whom hypertrophic cardiomyopathy is segregating as an autosomal dominant trait. In all those affected by the disease, a fragile site on the long arm of chromosome 16 was found, expressed with different frequencies, but the unaffected family members did not show this trait.

引用

页码：363 / 366

页数：4

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