MANAGING THE OLDER PATIENT WITH HYPERTENSION

被引：3

作者：

APPLEGATE, WB

机构：

[1] Department of Preventive Medicine, University of Tennessee, Memphis, TN, 38163

来源：

AMERICAN JOURNAL OF HYPERTENSION | 1993年 / 6卷 / 07期

基金：

英国医学研究理事会;

关键词：

HYPERTENSION; ELDERLY; DRUG TREATMENT; CARDIOVASCULAR DISEASE; STROKE;

D O I：

10.1093/ajh/6.7.277S

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

In elderly patients, elevation of systolic blood pressure represents a more serious risk than elevation of diastolic blood pressure. Major trials of antihypertensive therapy in the elderly include the Systolic Hypertension in the Elderly Program, the Swedish Trial of Older Patients with Hypertension, the Medical Research Council Trial, and the Veterans Affairs Cooperative Study Group. Results of these trials indicate that, even for very elderly patients, reducing blood pressure reduces both morbidity and mortality from stroke and cardiac disease. Diuretics and calcium antagonists stand out as particularly efficacious in elderly hypertensive patients. Beta-Adrenergic blockers and angiotensin converting enzyme inhibitors may be less suitable in this patient population. Studies of the effects of antihypertensive therapy on the quality of life indicate that elderly patients can easily tolerate efficacious doses of antihypertensive drugs.

引用

页码：S277 / S282

页数：6

共 21 条

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