PREPARATION AND CHARACTERIZATION OF LYMPHOCYTE-ACTIVATING FACTOR (LAF) FROM ACUTE MONOCYTIC AND MYELOMONOCYTIC LEUKEMIA-CELLS

被引：74

作者：

LACHMAN, LB ^{[1
]}

MOORE, JO ^{[1
]}

METZGAR, RS ^{[1
]}

机构：

[1] DUKE UNIV,MED CTR,DEPT MED,DIV HEMATOL,DURHAM,NC 27710

来源：

CELLULAR IMMUNOLOGY | 1978年 / 41卷 / 01期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0008-8749(78)80040-9

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Leukemia cells from acute monocytic and myelomonocytic patients undergoing leukophoresis have been used to prepare large quantities of lymphocyte-activating factor (LAF). The chemical properties of normal leukocyte LAF and leukemia cell LAF from a single donor for industrial-scale purification. The human histiocytic lymphoma cell line U937 was also evaluated as a possible source of LAF. Although exhibiting several monocyte-specific properties, the U937 cell line failed to release LAF. © 1978 Academic Press, Inc. All rights reserved.

引用

页码：199 / 206

页数：8

共 12 条

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[8] PREPARATION OF LYMPHOCYTE-ACTIVATING FACTOR FROM CONTINUOUS MURINE MACROPHAGE CELL LINES
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[J]. CELLULAR IMMUNOLOGY, 1977, 34 (02) : 416 - 419
[9] LACHMAN LB, UNPUBLISHED
[10] LACHMAN LB, 1977, J IMMUNOL, V11, P2019

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